SSX1

Across TCGA patient cohorts, SSX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,619 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SSX1-associated GO terms across cancer lineages are Protein localization to chromosome, centromeric region, Positive regulation of cell cycle phase transition, and Cell cycle DNA replication. Each is linked with SSX1 in more than 11 cancer types. Because this analysis shows association rather than direction, both SSX1-to-partner and partner-to-SSX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to chromosome, centromeric region grouped by SSX1-low versus SSX1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SSX1→partner) and Y-score (partner→SSX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Protein localization to chromosome, centromeric region →	+0.060	+0.406	<.001	.002	3	12
STAD	Positive regulation of cell cycle phase transition →	+0.085	+0.780	<.001	<.001	3	11
STAD	Cell cycle DNA replication →	+0.092	+0.815	<.001	<.001	2	12
STAD	Regulation of metaphase plate congression →	+0.087	+0.745	<.001	<.001	3	11
STAD	Positive regulation of mitotic cell cycle spindle assembly checkpoint →	+0.088	+0.703	<.001	<.001	3	11
STAD	Positive regulation of cell cycle checkpoint →	+0.088	+0.749	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,619 associations by consensus.

Protein localization to chromosome, centromeric region by SSX1 expression — STAD

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