SSUH2

Across TCGA cell cohorts, SSUH2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SSUH2-associated genes across cancer lineages are FAM205A, AMELY, and GSG1L2. Each is linked with SSUH2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SSUH2-to-partner and partner-to-SSUH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM205A grouped by SSUH2-low versus SSUH2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSUH2→partner) and Y-score (partner→SSUH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FAM205A →	+0.020	+3.614	<.001	.006	3	1
LARGE_INTESTINE	AMELY →	+0.030	+4.022	<.001	.006	3	1
BLOOD_Leukemia	GSG1L2 →	+0.043	+4.969	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

FAM205A by SSUH2 expression — LARGE_INTESTINE

Explore this box plot interactively →