SSU72P8

Across TCGA patient cohorts, SSU72P8 mutation is significantly associated with the RNA expression of many other genes, with 680 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SSU72P8-associated genes across cancer lineages are RNU6-441P, SPTSSA, and UQCRFS1P3. Each is linked with SSU72P8 in more than 1 cancer types. Because this analysis shows association rather than direction, both SSU72P8-to-partner and partner-to-SSU72P8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-441P grouped by SSU72P8-low versus SSU72P8-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSU72P8→partner) and Y-score (partner→SSU72P8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-441P →	+0.138	+3.885	<.001	.008	3	2
LUSC	SPTSSA →	+0.712	+3.471	.008	.002	3	2
SKCM	UQCRFS1P3 →	+0.060	+3.302	.008	.009	3	2
UCEC	ESS2 →	+0.340	+3.711	.004	<.001	3	1
UCEC	CRYBB2P1 →	+0.610	+3.385	.001	.004	3	1
UCEC	FBXO7 →	+0.449	+3.721	.006	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 680 associations by consensus.

RNU6-441P by SSU72P8 expression — UCEC

Explore this box plot interactively →