SSU72

Across TCGA pan-cancer cohorts, SSU72 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SSU72 data layer compared with 24 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SSU72 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SSU72 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

LUAD, CCRCC, and OV are the cancer types where SSU72 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	All	0.975	0.629	.004	24	view →
CCRCC	DFS	Median	All	0.575	0.854	.022	5	view →
OV	DFS	Median	All	0.623	1.000	.008	4	view →
PDAC	OS	Quartile	II,III,IV	0.360	0.648	.025	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SSU72–LUAD (DFS)

Open the LUAD breakdown →