SSTR5

Across TCGA cell cohorts, SSTR5 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,723 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SSTR5-associated GO terms across cancer lineages are Cytoplasmic translation, Somatostatin receptor signaling pathway, and Somatostatin signaling pathway. Each is linked with SSTR5 in more than 8 cancer types. Because this analysis shows association rather than direction, both SSTR5-to-partner and partner-to-SSTR5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translation grouped by SSTR5-low versus SSTR5-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SSTR5→partner) and Y-score (partner→SSTR5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cytoplasmic translation →	+0.053	+0.530	.006	<.001	3	8
STOMACH	Somatostatin receptor signaling pathway →	+1.352	+2.448	.002	.003	1	9
STOMACH	Somatostatin signaling pathway →	+1.352	+2.448	.002	.003	1	9
BREAST	Purine nucleoside triphosphate biosynthetic process →	+0.079	+0.334	<.001	.004	3	7
BREAST	Purine ribonucleoside triphosphate biosynthetic process →	+0.079	+0.334	<.001	.004	3	7
LUNG_SCLC	Aldosterone biosynthetic process →	+1.228	+1.093	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,723 associations by consensus.

Cytoplasmic translation by SSTR5 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →