SSTR5

Across TCGA cell cohorts, SSTR5 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SSTR5-associated genes across cancer lineages are DEFB4B, OR10T2, and C6orf118. Each is linked with SSTR5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SSTR5-to-partner and partner-to-SSTR5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEFB4B grouped by SSTR5-low versus SSTR5-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSTR5→partner) and Y-score (partner→SSTR5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	DEFB4B →	+0.234	+4.539	<.001	.007	3	1
BLOOD_Leukemia	OR10T2 →	+0.863	+4.276	<.001	.007	3	1
LARGE_INTESTINE	C6orf118 →	+0.130	+3.115	<.001	.004	3	1
LARGE_INTESTINE	TBR1 →	+0.042	+3.333	<.001	.009	3	1
LARGE_INTESTINE	OR1L6 →	+0.015	+3.700	<.001	.009	3	1
LARGE_INTESTINE	TBC1D28 →	+0.095	+3.115	.002	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

DEFB4B by SSTR5 expression — BLOOD_Leukemia

Explore this box plot interactively →