SSTR5-AS1

Across TCGA pan-cancer cohorts, SSTR5-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated SSTR5-AS1 data layer compared with 1 for mutation status.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher SSTR5-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated SSTR5-AS1 expression acts as an unfavorable survival marker, although some lineages such as ACC and LGG show a favorable association.

ACC, ESCA, and LGG are the cancer types where SSTR5-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.796	0.429	<.001	82	view →
ESCA	DFS	Median	II,III,IV	0.238	0.498	<.001	48	view →
LGG	OS	Median	All	0.887	0.734	<.001	43	view →
DLBC	DFS	Tertile	IV	0.120	0.683	.001	42	view →
READ	OS	Tertile	All	0.973	0.839	.007	35	view →
STAD	OS	Tertile	III,IV	0.308	0.518	.021	19	view →
PAAD	DFS	Tertile	All	0.436	0.253	.008	19	view →
THCA	DFS	Quartile	II,III,IV	0.644	0.933	.002	19	view →
HNSC	DFS	Median	IV	0.712	0.569	.009	18	view →
CHOL	DFS	Median	II,III,IV	0.111	0.528	.016	12	view →
TGCT	DFS	Quartile	All	0.713	0.892	.018	8	view →
UCEC	OS	Quartile	All	0.898	0.943	.013	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

SSTR5-AS1–ACC (DFS)

Open the ACC breakdown →