SSTR4

Across TCGA patient cohorts, SSTR4 protein abundance is significantly associated with the RNA expression of many other genes, with 860 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SSTR4-associated genes across cancer lineages are TOP3B, APOL1, and HDAC10. Each is linked with SSTR4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SSTR4-to-partner and partner-to-SSTR4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SSTR4 versus TOP3B in UCEC, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSTR4→partner) and Y-score (partner→SSTR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TOP3B →	-0.230	-0.314	.002	.007	3	1
UCEC	APOL1 →	+0.915	+0.355	.001	.001	3	1
UCEC	HDAC10 →	-0.252	-0.518	.001	<.001	3	1
UCEC	DDHD1 →	-0.474	-0.471	<.001	<.001	3	1
UCEC	SIX4 →	-0.443	-0.344	.006	.002	3	1
UCEC	SRPX →	+0.854	+0.395	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 860 associations by consensus.

SSTR4 vs TOP3B — UCEC

Explore this scatter interactively →