SSTR4

Across TCGA patient cohorts, SSTR4 protein abundance is significantly associated with the protein abundance of many other proteins, with 2,552 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SSTR4-associated proteins across cancer lineages are VANGL2_S315, WAPL_S461, and WASL_Y256. Each is linked with SSTR4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SSTR4-to-partner and partner-to-SSTR4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SSTR4 versus VANGL2_S315 in UCEC, with a Pearson correlation of -0.72.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SSTR4→partner) and Y-score (partner→SSTR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	VANGL2_S315 →	-0.536	-0.825	.001	<.001	3	1
UCEC	WAPL_S461 →	-0.751	-0.633	<.001	<.001	3	1
UCEC	WASL_Y256 →	+1.471	+0.660	<.001	<.001	3	1
UCEC	WDFY3 →	+0.212	+0.455	<.001	.002	3	1
UCEC	WDR44_S262 →	+0.654	+0.509	<.001	<.001	3	1
UCEC	WDR45 →	+0.280	+0.349	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,552 associations by consensus.

SSTR4 vs VANGL2_S315 — UCEC

Explore this scatter interactively →