SSTR4

Across TCGA patient cohorts, SSTR4 mutation is significantly associated with the immune_cell of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SSTR4-associated genes across cancer lineages are MPP, Erythrocytes, and Th2 cells. Each is linked with SSTR4 in more than 3 cancer types. Because this analysis shows association rather than direction, both SSTR4-to-partner and partner-to-SSTR4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MPP grouped by SSTR4-low versus SSTR4-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSTR4→partner) and Y-score (partner→SSTR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	MPP →	+0.024	+2.809	<.001	.040	3	4
STAD	Erythrocytes →	+0.018	+3.164	.001	.032	3	2
UCEC	Th2 cells →	+0.137	+1.493	.028	.035	3	2
SKCM	HSC →	-0.090	-3.290	.035	.010	3	1
SKCM	Th1 cells →	+0.093	+3.009	.039	.019	3	1
LUAD	CMP →	+0.020	+1.577	<.001	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

MPP by SSTR4 expression — STAD

Explore this box plot interactively →