SSTR3

Across TCGA pan-cancer cohorts, SSTR3 Mutation is linked to patient survival in 11 of 34 cancer types, making it a survival-associated SSTR3 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher SSTR3 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated SSTR3 expression acts as an unfavorable survival marker.

OV, THYM, and COAD are the cancer types where SSTR3 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	DFS	Median	II,III,IV	0.182	0.541	.011	30	view →
THYM	OS	Median	All	0.039	0.928	<.001	24	view →
COAD	OS	Median	All	0.391	0.874	.001	14	view →
KIRC	OS	Median	All	0.249	0.805	.010	12	view →
BLCA	OS	Median	IV	0.141	0.593	<.001	12	view →
SKCM	OS	Median	II,III,IV	0.269	0.845	<.001	12	view →
LUSC	DFS	Median	II,III,IV	0.417	0.724	.006	9	view →
LGG	OS	Median	All	0.208	0.889	<.001	6	view →
ACC	DFS	Median	All	0.195	0.748	.003	6	view →
PRAD	OS	Median	All	0.145	0.883	<.001	6	view →
LIHC	OS	Median	All	0.164	0.688	.030	6	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

SSTR3–OV (DFS)

Open the OV breakdown →