SSTR3

Across TCGA patient cohorts, SSTR3 mutation is significantly associated with the RNA expression of many other genes, with 1,662 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SSTR3-associated genes across cancer lineages are FANCA, ALDH18A1, and RPL32P36. Each is linked with SSTR3 in more than 2 cancer types. Because this analysis shows association rather than direction, both SSTR3-to-partner and partner-to-SSTR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FANCA grouped by SSTR3-low versus SSTR3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSTR3→partner) and Y-score (partner→SSTR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FANCA →	+0.631	+2.736	<.001	<.001	3	3
UCEC	ALDH18A1 →	+0.422	+2.258	.006	.001	3	3
HNSC	RPL32P36 →	+0.172	+3.602	<.001	.002	3	2
HNSC	OSBPL9P2 →	+0.032	+3.546	<.001	.002	3	2
HNSC	MIR8066 →	+0.284	+3.548	<.001	.005	3	2
UCEC	HARBI1 →	+0.357	+3.743	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,662 associations by consensus.

FANCA by SSTR3 expression — UCEC

Explore this box plot interactively →