SSTR3

Across TCGA cell cohorts, SSTR3 RNA expression is significantly associated with the go_rna of many other GO terms, with 923 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SSTR3-associated GO terms across cancer lineages are Hormone-mediated apoptotic signaling pathway, Nuclear export, and Regulation of axon extension. Each is linked with SSTR3 in more than 6 cancer types. Because this analysis shows association rather than direction, both SSTR3-to-partner and partner-to-SSTR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Hormone-mediated apoptotic signaling pathway grouped by SSTR3-low versus SSTR3-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SSTR3→partner) and Y-score (partner→SSTR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Hormone-mediated apoptotic signaling pathway →	+1.559	+3.371	<.001	<.001	3	7
LUNG_NSCLC_LUAD	Nuclear export →	+0.041	+0.015	.005	.001	3	6
OESOPHAGUS	Regulation of axon extension →	+0.102	+0.040	<.001	.008	3	5
PANCREAS	Regulation of cellular response to heat →	+0.119	+0.056	<.001	.001	3	5
OESOPHAGUS	Negative regulation of binding →	+0.092	+0.057	.001	.006	3	5
BREAST	Regulation of mRNA splicing, via spliceosome →	+0.054	+0.020	.007	.008	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 923 associations by consensus.

Hormone-mediated apoptotic signaling pathway by SSTR3 expression — BLOOD_Myeloma

Explore this box plot interactively →