SSTR3

Across TCGA cell cohorts, SSTR3 mutation is significantly associated with the RNA expression of many other genes, with 43 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SSTR3-associated genes across cancer lineages are DCLK3, TCEAL5, and TAS2R39. Each is linked with SSTR3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SSTR3-to-partner and partner-to-SSTR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DCLK3 grouped by SSTR3-low versus SSTR3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSTR3→partner) and Y-score (partner→SSTR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	DCLK3 →	+0.244	+3.769	<.001	.008	3	2
BLOOD_Leukemia	TCEAL5 →	+0.861	+3.917	<.001	.006	3	2
BLOOD_Leukemia	TAS2R39 →	+0.051	+4.339	<.001	.002	3	2
BREAST	TMEM207 →	+0.162	+4.672	<.001	.002	3	2
BONE	OLIG1 →	+1.853	+4.000	<.001	.008	3	1
BONE	PRR23A →	+0.058	+4.672	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

DCLK3 by SSTR3 expression — BLOOD_Leukemia

Explore this box plot interactively →