SSTR1

Across TCGA pan-cancer cohorts, SSTR1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SSTR1 data layer compared with 25 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher SSTR1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated SSTR1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and CCRCC show a favorable association.

PDAC, CCRCC, and GBM are the cancer types where SSTR1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Tertile	All	0.688	0.166	.002	22	view →
CCRCC	OS	Median	III,IV	0.914	0.505	.002	17	view →
GBM	DFS	Quartile	All	0.456	0.228	.039	3	view →
UCEC	OS	Median	All	0.860	1.000	.039	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SSTR1–PDAC (OS)

Open the PDAC breakdown →