SSTR1

Across TCGA pan-cancer cohorts, SSTR1 mass-spec protein differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of SSTR1’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where SSTR1 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types SSTR1 is over-expressed in tumor.

LSCC, LUAD, and PDAC are the cancer types where SSTR1 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SSTR1 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LSCC	Female	II,III,IV	+0.964	<.001	9	view →
LUAD	Male	III,IV	+0.773	<.001	8	view →
PDAC	Male	II,III,IV	+0.942	<.001	6	view →
HNSC	All	All	+0.420	.001	6	view →
CCRCC	Male	All	+0.317	<.001	5	view →
OV	All	All	+1.600	.005	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

SSTR1–LSCC

Open the LSCC breakdown →