SSTR1

Across TCGA cell cohorts, SSTR1 mutation is significantly associated with the RNA expression of many other genes, with 32 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SSTR1-associated genes across cancer lineages are GZMK, PAX1, and BTBD16. Each is linked with SSTR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SSTR1-to-partner and partner-to-SSTR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GZMK grouped by SSTR1-low versus SSTR1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSTR1→partner) and Y-score (partner→SSTR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GZMK →	+0.414	+4.037	.008	.004	3	1
BLOOD_Leukemia	PAX1 →	+0.042	+4.060	<.001	.003	3	1
BLOOD_Leukemia	BTBD16 →	+0.122	+3.959	<.001	.005	3	1
BLOOD_Leukemia	RHCG →	+0.103	+3.729	<.001	.009	3	1
BLOOD_Leukemia	TACR3 →	+0.032	+5.475	<.001	<.001	3	1
BLOOD_Leukemia	OR1L3 →	+0.050	+4.691	.009	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

GZMK by SSTR1 expression — BLOOD_Leukemia

Explore this box plot interactively →