SST

Across TCGA pan-cancer cohorts, SST mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SST data layer compared with 18 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SST mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SST expression acts as an unfavorable survival marker, although some lineages such as CCRCC and PDAC show a favorable association.

LUAD, CCRCC, and PDAC are the cancer types where SST mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	All	0.441	0.880	.004	33	view →
CCRCC	OS	Tertile	All	1.000	0.639	.012	6	view →
PDAC	OS	Median	III,IV	1.000	0.537	.008	6	view →
GBM	DFS	Tertile	All	0.874	0.683	.020	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SST–LUAD (DFS)

Open the LUAD breakdown →