SSRP1

Across TCGA pan-cancer cohorts, SSRP1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated SSRP1 data layer compared with 25 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SSRP1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated SSRP1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

LUAD, LSCC, and UCEC are the cancer types where SSRP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	III,IV	0.975	0.544	.001	34	view →
LSCC	DFS	Median	II,III,IV	0.862	0.504	.002	19	view →
UCEC	DFS	Tertile	II,III,IV	0.524	0.916	.035	12	view →
HNSC	DFS	Tertile	IV	0.747	0.932	.014	7	view →
CCRCC	OS	Median	IV	1.000	0.202	.034	4	view →
PDAC	DFS	Median	All	0.801	0.721	.019	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

SSRP1–LUAD (DFS)

Open the LUAD breakdown →