SSRP1

Across TCGA patient cohorts, SSRP1 mutation is significantly associated with the RNA expression of many other genes, with 2,601 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SSRP1-associated genes across cancer lineages are MIR549A, RNA5SP198, and POTEH-AS1. Each is linked with SSRP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SSRP1-to-partner and partner-to-SSRP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR549A grouped by SSRP1-low versus SSRP1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSRP1→partner) and Y-score (partner→SSRP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR549A →	+0.336	+5.342	<.001	.002	3	2
CESC	RNA5SP198 →	+0.305	+5.144	<.001	.003	3	2
CESC	POTEH-AS1 →	+0.023	+4.669	<.001	.007	3	2
BRCA	TAAR3P →	+0.149	+4.290	.008	.008	3	2
SKCM	IGLVI-38 →	+0.109	+3.449	.001	.009	3	2
SKCM	MIR4325 →	+0.217	+6.228	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,601 associations by consensus.

MIR549A by SSRP1 expression — CESC

Explore this box plot interactively →