SSRP1

Across TCGA cell cohorts, SSRP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,815 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SSRP1-associated GO terms across cancer lineages are DNA-templated DNA replication, DNA strand elongation involved in DNA replication, and Mitotic sister chromatid segregation. Each is linked with SSRP1 in more than 19 cancer types. Because this analysis shows association rather than direction, both SSRP1-to-partner and partner-to-SSRP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated DNA replication grouped by SSRP1-low versus SSRP1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SSRP1→partner) and Y-score (partner→SSRP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	DNA-templated DNA replication →	+0.170	+1.174	<.001	<.001	3	20
LUNG_NSCLC_LUSC	DNA strand elongation involved in DNA replication →	+0.165	+0.737	<.001	.002	3	19
BONE	Mitotic sister chromatid segregation →	+0.140	+1.126	.001	<.001	3	19
BONE	Chromosome segregation →	+0.120	+0.940	.003	.001	3	19
BONE	Mitotic chromosome condensation →	+0.227	+1.267	<.001	<.001	3	19
BONE	Double-strand break repair via break-induced replication →	+0.305	+1.347	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,815 associations by consensus.

DNA-templated DNA replication by SSRP1 expression — BONE

Explore this box plot interactively →