SSRP1

Across TCGA cell cohorts, SSRP1 protein abundance is significantly associated with the go_rna of many other GO terms, with 2,373 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SSRP1-associated GO terms across cancer lineages are Regulation of JUN kinase activity, Regulation of oxidative phosphorylation, and Protein insertion into mitochondrial inner membrane from matrix. Each is linked with SSRP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both SSRP1-to-partner and partner-to-SSRP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of JUN kinase activity grouped by SSRP1-low versus SSRP1-high in OVARY.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SSRP1→partner) and Y-score (partner→SSRP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of JUN kinase activity →	+0.228	+1.170	.004	.003	3	3
BLOOD_Lymphoma	Regulation of oxidative phosphorylation →	-0.124	-1.274	<.001	.003	3	3
SKIN	Protein insertion into mitochondrial inner membrane from matrix →	-0.127	-2.103	.005	.006	3	3
LUNG_SCLC	Response to auditory stimulus →	-0.121	-0.995	.003	<.001	3	2
STOMACH	Pyrimidine nucleoside monophosphate metabolic process →	+0.197	+1.553	.002	.009	3	2
STOMACH	Pyrimidine nucleoside monophosphate biosynthetic process →	+0.146	+1.553	.006	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,373 associations by consensus.

Regulation of JUN kinase activity by SSRP1 expression — OVARY

Explore this box plot interactively →