SSRP1

Across TCGA cell cohorts, SSRP1 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible SSRP1-associated genes across cancer lineages are CCL21, TEX43, and TEX50. Each is linked with SSRP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SSRP1-to-partner and partner-to-SSRP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCL21 grouped by SSRP1-low versus SSRP1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSRP1→partner) and Y-score (partner→SSRP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	CCL21 →	+0.152	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	TEX43 →	+0.094	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	TEX50 →	+0.045	+5.643	<.001	.002	3	1
LARGE_INTESTINE	RFX4 →	+0.035	+3.029	<.001	.003	3	1
LARGE_INTESTINE	OR10W1 →	+0.012	+3.240	<.001	.004	3	1
BLOOD_Leukemia	SPRR1A →	+0.287	+5.201	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

CCL21 by SSRP1 expression — BLOOD_Lymphoma

Explore this box plot interactively →