SSR4P1

Across TCGA patient cohorts, SSR4P1 mutation is significantly associated with the RNA expression of many other genes, with 108 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SSR4P1-associated genes across cancer lineages are MIR3193, SEC22B, and MIR4754. Each is linked with SSR4P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SSR4P1-to-partner and partner-to-SSR4P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3193 grouped by SSR4P1-low versus SSR4P1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSR4P1→partner) and Y-score (partner→SSR4P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR3193 →	+0.655	+2.838	<.001	.003	3	1
UCEC	SEC22B →	+0.716	+3.191	<.001	.009	3	1
UCEC	MIR4754 →	+0.734	+3.664	.003	.005	3	1
UCEC	MIA-RAB4B →	+0.113	+2.448	<.001	.008	3	1
UCEC	URGCP-MRPS24 →	+0.360	+3.643	<.001	.003	3	1
UCEC	LINC02348 →	+0.379	+3.077	.005	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 108 associations by consensus.

MIR3193 by SSR4P1 expression — UCEC

Explore this box plot interactively →