SSR4P1

Across TCGA patient cohorts, SSR4P1 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SSR4P1-associated genes across cancer lineages are Class-switched memory B-cells, Endothelial cells, and lymphatic Endothelial cells. Each is linked with SSR4P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SSR4P1-to-partner and partner-to-SSR4P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Class-switched memory B-cells grouped by SSR4P1-low versus SSR4P1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSR4P1→partner) and Y-score (partner→SSR4P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Class-switched memory B-cells →	-0.063	-3.169	.044	.020	1	1
UCEC	Endothelial cells →	-0.044	-3.127	.034	.020	1	1
UCEC	lymphatic Endothelial cells →	-0.028	-3.116	.034	.020	1	1
UCEC	mv Endothelial cells →	-0.027	-3.159	.036	.020	1	1
UCEC	Plasma cells →	-0.027	-3.127	.023	.020	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Class-switched memory B-cells by SSR4P1 expression — UCEC

Explore this box plot interactively →