SSR2

Across TCGA patient cohorts, SSR2 mutation is significantly associated with the RNA expression of many other genes, with 455 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SSR2-associated genes across cancer lineages are SNRPCP20, LINC00352, and TDGF1P1. Each is linked with SSR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SSR2-to-partner and partner-to-SSR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNRPCP20 grouped by SSR2-low versus SSR2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSR2→partner) and Y-score (partner→SSR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SNRPCP20 →	+0.280	+3.661	.002	.002	3	2
CESC	LINC00352 →	+0.216	+4.996	<.001	.002	3	2
LIHC	TDGF1P1 →	+0.087	+5.355	<.001	.005	3	2
UCEC	RNU6-1064P →	+0.596	+1.931	<.001	.009	3	2
UCEC	RPL6P4 →	+0.169	+3.408	.003	.005	3	2
UCEC	RPS27AP14 →	+0.084	+3.123	.003	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 455 associations by consensus.

SNRPCP20 by SSR2 expression — COAD

Explore this box plot interactively →