SSR2

Across TCGA patient cohorts, SSR2 mutation is significantly associated with the total protein of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SSR2-associated genes across cancer lineages are p21, p27, and XBP1. Each is linked with SSR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SSR2-to-partner and partner-to-SSR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p21 grouped by SSR2-low versus SSR2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSR2→partner) and Y-score (partner→SSR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p21 →	+0.226	+2.321	.019	.035	3	1
UCEC	p27 →	+0.291	+3.169	.007	.019	3	1
UCEC	XBP1 →	-0.231	-3.000	.001	.036	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

p21 by SSR2 expression — UCEC

Explore this box plot interactively →