SSR2

Across TCGA cell cohorts, SSR2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SSR2-associated genes across cancer lineages are MAGEB5 and OR10W1. Each is linked with SSR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SSR2-to-partner and partner-to-SSR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB5 grouped by SSR2-low versus SSR2-high in LUNG_NSCLC_LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSR2→partner) and Y-score (partner→SSR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	MAGEB5 →	+0.033	+4.643	<.001	.008	3	1
LARGE_INTESTINE	OR10W1 →	+0.022	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

MAGEB5 by SSR2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →