SSR1

Across TCGA patient cohorts, SSR1 mutation is significantly associated with the RNA expression of many other genes, with 1,174 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SSR1-associated genes across cancer lineages are LINC02644, SLC6A14P1, and CYCTP. Each is linked with SSR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SSR1-to-partner and partner-to-SSR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02644 grouped by SSR1-low versus SSR1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSR1→partner) and Y-score (partner→SSR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC02644 →	+0.132	+2.577	<.001	.006	3	2
CESC	SLC6A14P1 →	+0.113	+5.201	<.001	.007	3	1
CESC	CYCTP →	+0.307	+5.306	<.001	.006	3	1
CESC	LINC01898 →	+0.032	+6.569	<.001	.001	3	1
CESC	MIR3925 →	+0.521	+6.144	<.001	.001	3	1
UCEC	LAMTOR1 →	+0.392	+3.098	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,174 associations by consensus.

LINC02644 by SSR1 expression — UCEC

Explore this box plot interactively →