SSR1

Across TCGA cell cohorts, SSR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,354 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SSR1-associated GO terms across cancer lineages are Regulation of peptidyl-lysine crotonylation, Negative regulation of peptidyl-lysine crotonylation, and Post-translational protein targeting to membrane, translocation. Each is linked with SSR1 in more than 16 cancer types. Because this analysis shows association rather than direction, both SSR1-to-partner and partner-to-SSR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of peptidyl-lysine crotonylation grouped by SSR1-low versus SSR1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SSR1→partner) and Y-score (partner→SSR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Regulation of peptidyl-lysine crotonylation →	+0.186	+0.976	<.001	.008	2	17
LIVER	Negative regulation of peptidyl-lysine crotonylation →	+0.186	+0.976	<.001	.008	2	17
UPPER_AERODIGESTIVE_TRACT	Post-translational protein targeting to membrane, translocation →	+0.108	+0.772	<.001	<.001	3	15
CNS	Protein N-linked glycosylation →	+0.077	+0.739	<.001	<.001	3	13
SOFT_TISSUE	Cotranslational protein targeting to membrane →	+0.117	+0.919	<.001	.001	3	13
LUNG_SCLC	Positive regulation of protein exit from endoplasmic reticulum →	+0.119	+0.681	.001	.005	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,354 associations by consensus.

Regulation of peptidyl-lysine crotonylation by SSR1 expression — LIVER

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