SSNA1

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, SSNA1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SSNA1 data layer compared with 25 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher SSNA1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SSNA1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LSCC show a favorable association.

COAD, CCRCC, and UCEC are the cancer types where SSNA1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
COADDFSMedianAll0.9161.000.01060view →
CCRCCDFSMedianAll0.8880.974.0214view →
UCECOSMedianII,III,IV1.0000.675.0304view →
LSCCDFSMedianAll0.8940.518.0321view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SSNA1–COAD (DFS)

Kaplan–Meier survival curve for SSNA1 mass-spec protein-high vs -low samples in COAD.

Open the COAD breakdown →

Exploration