SSH2

Across TCGA patient cohorts, SSH2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,086 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SSH2-associated proteins across cancer lineages are CLIC2, DOCK11, and TAOK1. Each is linked with SSH2 in more than 4 cancer types. Because this analysis shows association rather than direction, both SSH2-to-partner and partner-to-SSH2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SSH2 versus CLIC2 in LSCC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SSH2→partner) and Y-score (partner→SSH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CLIC2 →	+0.487	+0.519	<.001	<.001	3	5
OV	DOCK11 →	+0.352	+0.472	.002	.004	3	5
BRCA	TAOK1 →	+0.293	+0.560	<.001	<.001	3	4
HNSC	TM6SF1 →	+0.733	+0.811	.001	.006	2	5
GBM	PIK3AP1 →	+0.746	+0.772	<.001	<.001	3	4
GBM	PIP4K2A →	+0.382	+0.601	.003	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,086 associations by consensus.

SSH2 vs CLIC2 — LSCC

Explore this scatter interactively →