SSBP4

Across TCGA pan-cancer cohorts, SSBP4 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SSBP4 data layer compared with 22 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher SSBP4 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SSBP4 expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

UCEC, HNSC, and CCRCC are the cancer types where SSBP4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	II,III,IV	0.469	0.944	.003	20	view →
HNSC	OS	Median	III,IV	0.589	0.776	.022	6	view →
CCRCC	DFS	Median	All	0.878	0.980	.015	5	view →
PDAC	DFS	Median	All	0.612	0.379	.025	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SSBP4–UCEC (DFS)

Open the UCEC breakdown →