SSBP4

Across TCGA patient cohorts, SSBP4 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. ESCA shows the largest number of these associations.

The most reproducible SSBP4-associated genes across cancer lineages are CD8+ Tem and NK cells. Each is linked with SSBP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both SSBP4-to-partner and partner-to-SSBP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ Tem grouped by SSBP4-low versus SSBP4-high in ESCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SSBP4→partner) and Y-score (partner→SSBP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	CD8+ Tem →	+0.018	+5.285	<.001	.049	3	1
ESCA	NK cells →	+0.002	+5.709	.002	.037	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CD8+ Tem by SSBP4 expression — ESCA

Explore this box plot interactively →