SSBP4

Across TCGA cell cohorts, SSBP4 protein abundance is significantly associated with the go_rna of many other GO terms, with 557 significant associations in total. BLOOD_Myeloma shows the largest number of these associations.

The most reproducible SSBP4-associated GO terms across cancer lineages are Regulation of signal transduction by p53 class mediator, Regulation of cAMP/PKA signal transduction, and Regulation of complement activation. Each is linked with SSBP4 in more than 3 cancer types. Because this analysis shows association rather than direction, both SSBP4-to-partner and partner-to-SSBP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of signal transduction by p53 class mediator grouped by SSBP4-low versus SSBP4-high in LARGE_INTESTINE.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SSBP4→partner) and Y-score (partner→SSBP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of signal transduction by p53 class mediator →	-0.074	-1.543	.002	.005	3	4
OVARY	Regulation of cAMP/PKA signal transduction →	-0.121	-2.028	.002	.001	3	3
OVARY	Regulation of complement activation →	-0.222	-2.028	.001	.001	3	3
BLOOD_Myeloma	Pyrimidine-containing compound biosynthetic process →	+0.111	+1.424	.001	.003	3	3
BLOOD_Myeloma	Protein destabilization →	-0.067	-1.406	.008	.004	2	4
BLOOD_Myeloma	Positive regulation of fibrinolysis →	+1.853	+1.424	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 557 associations by consensus.

Regulation of signal transduction by p53 class mediator by SSBP4 expression — LARGE_INTESTINE

Explore this box plot interactively →