Across TCGA pan-cancer cohorts, SSBP3P2 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of SSBP3P2’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where SSBP3P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SSBP3P2 is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.
BRCA, PRAD, and LUSC are the cancer types where SSBP3P2 tumor–normal differential expression is most reproducible.