SSBP3

Across TCGA pan-cancer cohorts, SSBP3 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated SSBP3 data layer compared with 23 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher SSBP3 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SSBP3 expression acts as an unfavorable survival marker, although some lineages such as COAD and LUAD show a favorable association.

HNSC, COAD, and LUAD are the cancer types where SSBP3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	IV	0.481	0.808	.001	27	view →
COAD	DFS	Median	All	1.000	0.886	.020	24	view →
LUAD	OS	Median	All	0.904	0.776	.006	14	view →
LSCC	OS	Tertile	III,IV	0.986	0.547	.007	10	view →
CCRCC	DFS	Tertile	All	0.838	1.000	.018	6	view →
PDAC	OS	Median	II,III,IV	0.385	0.618	.007	4	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

SSBP3–HNSC (DFS)

Open the HNSC breakdown →