SSBP2

Across TCGA pan-cancer cohorts, SSBP2 mass-spec protein is linked to patient survival in 8 of 34 cancer types, making it a survival-associated SSBP2 data layer compared with 29 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher SSBP2 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SSBP2 expression acts as an unfavorable survival marker, although some lineages such as PDAC and OV show a favorable association.

LSCC, PDAC, and OV are the cancer types where SSBP2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Quartile	All	0.582	0.868	.018	11	view →
PDAC	OS	Quartile	All	0.626	0.306	.009	9	view →
OV	DFS	Tertile	All	0.884	0.567	.030	8	view →
UCEC	OS	Tertile	II,III,IV	0.572	1.000	.037	8	view →
HNSC	OS	Median	II,III,IV	0.922	1.000	.016	8	view →
CCRCC	DFS	Quartile	III,IV	0.945	0.305	.006	5	view →
LUAD	DFS	Median	III,IV	0.409	0.941	.010	3	view →
GBM	OS	Tertile	All	0.609	0.359	.039	1	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

SSBP2–LSCC (DFS)

Open the LSCC breakdown →