SSBP2

Across TCGA cell cohorts, SSBP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,697 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SSBP2-associated GO terms across cancer lineages are Pyramidal neuron differentiation, Regulation of transcription initiation by RNA polymerase II, and Endoplasmic reticulum to Golgi vesicle-mediated transport. Each is linked with SSBP2 in more than 9 cancer types. Because this analysis shows association rather than direction, both SSBP2-to-partner and partner-to-SSBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pyramidal neuron differentiation grouped by SSBP2-low versus SSBP2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SSBP2→partner) and Y-score (partner→SSBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Pyramidal neuron differentiation →	+0.126	+1.433	.005	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of transcription initiation by RNA polymerase II →	+0.073	+1.710	<.001	<.001	3	10
CNS	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.068	+1.465	<.001	<.001	3	10
BLOOD_Myeloma	Regulation of G0 to G1 transition →	+0.090	+1.580	<.001	.006	3	10
LIVER	Vesicle coating →	+0.092	+1.854	.005	.009	3	10
BREAST	Urokinase plasminogen activator signaling pathway →	-0.992	-1.386	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,697 associations by consensus.

Pyramidal neuron differentiation by SSBP2 expression — OVARY

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