SSBP1

Across TCGA pan-cancer cohorts, SSBP1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SSBP1 data layer compared with 23 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher SSBP1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SSBP1 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

CCRCC, LSCC, and LUAD are the cancer types where SSBP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	III,IV	0.361	0.765	.003	31	view →
LSCC	DFS	Quartile	II,III,IV	1.000	0.585	.008	9	view →
LUAD	DFS	Median	III,IV	0.409	0.941	.010	3	view →
PDAC	OS	Median	IV	0.491	0.836	.024	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SSBP1–CCRCC (DFS)

Open the CCRCC breakdown →