SSBP1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SSBP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,614 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible SSBP1-associated GO terms across cancer lineages are tRNA 5'-end processing, Protein insertion into mitochondrial membrane, and tRNA processing. Each is linked with SSBP1 in more than 13 cancer types. Because this analysis shows association rather than direction, both SSBP1-to-partner and partner-to-SSBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA 5'-end processing grouped by SSBP1-low versus SSBP1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SSBP1→partner) and Y-score (partner→SSBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTtRNA 5'-end processing →+0.128+1.151<.001<.001314
OVARYProtein insertion into mitochondrial membrane →+0.089+0.967<.001<.001314
UPPER_AERODIGESTIVE_TRACTtRNA processing →+0.059+0.993.001<.001314
UPPER_AERODIGESTIVE_TRACTtRNA 5'-leader removal →+0.121+1.017<.001<.001313
URINARY_TRACTsnoRNA guided rRNA pseudouridine synthesis →+0.103+0.798<.001.005313
SKINmRNA modification →+0.077+0.573<.001<.001313
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,614 associations by consensus.

tRNA 5'-end processing by SSBP1 expression — UPPER_AERODIGESTIVE_TRACT

Box plot of tRNA 5'-end processing in SSBP1-low vs SSBP1-high samples in UPPER_AERODIGESTIVE_TRACT.

Explore this box plot interactively →

Exploration