Across TCGA pan-cancer cohorts, SSBL3P RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of SSBL3P’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where SSBL3P RNA is repressed in tumor relative to normal tissue. In most cancer types SSBL3P is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.
BRCA, KIRC, and COAD are the cancer types where SSBL3P tumor–normal differential expression is most reproducible.