SS18L1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SS18L1 mutation is significantly associated with the RNA expression of many other genes, with 921 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SS18L1-associated genes across cancer lineages are RN7SL508P, H3P32, and PRAMEF33. Each is linked with SS18L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SS18L1-to-partner and partner-to-SS18L1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SS18L1→partner) and Y-score (partner→SS18L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADRN7SL508P →+0.543+3.289.002.00832
BLCAH3P32 →+0.103+5.177.006.00732
LUADPRAMEF33 →+0.015+5.523<.001.00132
SKCMGLYATL3 →+0.131+4.075<.001.00432
UCECSNORD90 →+0.357+2.617<.001<.00132
SKCMLINC01680 →+0.086+5.900<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 921 associations by consensus.

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