Across TCGA patient cohorts, SS18L1 mutation is significantly associated with the total protein of many other genes, with 19 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SS18L1-associated genes across cancer lineages are mTOR_pS2448, eEF2, and EGFR_pY1068. Each is linked with SS18L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SS18L1-to-partner and partner-to-SS18L1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SS18L1→partner) and Y-score (partner→SS18L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	mTOR_pS2448 →	-0.132	-3.302	.021	.010	3	2
UCEC	eEF2 →	+0.271	+3.169	.048	.018	3	1
UCEC	EGFR_pY1068 →	-0.254	-2.999	.008	.035	3	1
UCEC	ERK2 →	+0.208	+3.321	.004	.009	3	1
UCEC	FoxM1 →	+0.278	+1.874	.005	.049	3	1
UCEC	GATA6 →	-0.157	-3.307	.011	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Exploration

SS18L1 survival (RNA) · tumor vs normal (RNA) · all SS18L1 data types