Across TCGA cell cohorts, SS18L1 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SS18L1-associated genes across cancer lineages are HTR2A, PTPN5, and PLPPR4. Each is linked with SS18L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SS18L1-to-partner and partner-to-SS18L1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SS18L1→partner) and Y-score (partner→SS18L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	HTR2A →	+0.186	+3.084	.004	.002	3	1
LARGE_INTESTINE	PTPN5 →	+0.036	+3.754	<.001	.002	3	1
LARGE_INTESTINE	PLPPR4 →	+0.468	+3.887	<.001	.001	3	1
LARGE_INTESTINE	ELOVL4 →	+0.608	+3.443	.002	.009	3	1
LARGE_INTESTINE	ANKRD30BL →	+0.016	+3.632	<.001	<.001	3	1
LARGE_INTESTINE	HES3 →	+0.058	+3.632	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration

SS18L1 survival (RNA) · tumor vs normal (RNA) · all SS18L1 data types