SS18

Across TCGA cell cohorts, SS18 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,916 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SS18-associated GO terms across cancer lineages are Mitotic cytokinesis, Cytokinesis, and Regulation of metaphase/anaphase transition of cell cycle. Each is linked with SS18 in more than 13 cancer types. Because this analysis shows association rather than direction, both SS18-to-partner and partner-to-SS18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic cytokinesis grouped by SS18-low versus SS18-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SS18→partner) and Y-score (partner→SS18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Mitotic cytokinesis →	+0.072	+0.930	<.001	<.001	3	14
OVARY	Cytokinesis →	+0.065	+0.848	<.001	<.001	3	14
CNS	Regulation of metaphase/anaphase transition of cell cycle →	+0.111	+0.806	<.001	<.001	3	14
BREAST	Cell division →	+0.075	+0.728	<.001	.004	3	14
UPPER_AERODIGESTIVE_TRACT	DNA damage tolerance →	+0.088	+0.711	<.001	.006	3	14
CNS	Mitotic nuclear division →	+0.095	+0.745	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,916 associations by consensus.

Mitotic cytokinesis by SS18 expression — SOFT_TISSUE

Explore this box plot interactively →