Across TCGA patient cohorts, SRY RNA expression is significantly associated with the go_rna of many other GO terms, with 6,187 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible SRY-associated GO terms across cancer lineages are Skin epidermis development, Sequestering of actin monomers, and Desmosome organization. Each is linked with SRY in more than 8 cancer types. Because this analysis shows association rather than direction, both SRY-to-partner and partner-to-SRY results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SRY→partner) and Y-score (partner→SRY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Skin epidermis development →	+0.033	+0.105	<.001	<.001	3	9
LAML	Sequestering of actin monomers →	-0.085	-0.265	<.001	<.001	3	8
TGCT	Desmosome organization →	+0.103	+1.403	<.001	<.001	3	8
TGCT	Nephron development →	+0.042	+0.821	<.001	<.001	3	7
TGCT	Fibroblast proliferation →	+0.027	+0.685	<.001	<.001	3	7
TGCT	Negative regulation of epithelial cell proliferation →	+0.028	+1.060	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,187 associations by consensus.

Exploration

SRY survival (RNA) · tumor vs normal (RNA) · all SRY data types