Across TCGA cell cohorts, SRY RNA expression is significantly associated with the go_rna of many other GO terms, with 125 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SRY-associated GO terms across cancer lineages are Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, Virion assembly, and UDP-N-acetylglucosamine transmembrane transport. Each is linked with SRY in more than 1 cancer types. Because this analysis shows association rather than direction, both SRY-to-partner and partner-to-SRY results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SRY→partner) and Y-score (partner→SRY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.060	+0.009	.003	.003	3	2
BLOOD_Leukemia	Virion assembly →	+0.055	+0.009	.003	.003	3	2
BLOOD_Leukemia	UDP-N-acetylglucosamine transmembrane transport →	+0.076	+0.009	.002	.003	3	2
BLOOD_Leukemia	Cellular component disassembly →	+0.037	+0.009	<.001	.003	3	2
BLOOD_Leukemia	Multivesicular body assembly →	+0.075	+0.009	.001	.003	3	2
BLOOD_Leukemia	RNA destabilization →	+0.044	+0.012	.003	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 125 associations by consensus.

Exploration

SRY survival (RNA) · tumor vs normal (RNA) · all SRY data types