SRXN1

Across TCGA cell cohorts, SRXN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,697 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SRXN1-associated GO terms across cancer lineages are Response to thyroxine, Response to L-phenylalanine derivative, and Response to human chorionic gonadotropin. Each is linked with SRXN1 in more than 13 cancer types. Because this analysis shows association rather than direction, both SRXN1-to-partner and partner-to-SRXN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to thyroxine grouped by SRXN1-low versus SRXN1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SRXN1→partner) and Y-score (partner→SRXN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Response to thyroxine →	+0.267	+2.048	<.001	.001	3	14
LIVER	Response to L-phenylalanine derivative →	+0.211	+1.730	<.001	.002	2	14
LUNG_NSCLC_LUSC	Response to human chorionic gonadotropin →	+0.309	+2.257	<.001	<.001	3	13
BONE	Response to hepatocyte growth factor →	+0.148	+1.992	.001	.001	3	12
BONE	Cellular response to hepatocyte growth factor stimulus →	+0.151	+1.594	<.001	.001	3	12
LUNG_SCLC	Response to nitrosative stress →	+0.194	+2.926	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,697 associations by consensus.

Response to thyroxine by SRXN1 expression — OESOPHAGUS

Explore this box plot interactively →