SRSF9

Across TCGA patient cohorts, SRSF9 protein abundance is significantly associated with the RNA expression of many other genes, with 21,266 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SRSF9-associated genes across cancer lineages are SPPL3, POLE, and KMT5A. Each is linked with SRSF9 in more than 7 cancer types. Because this analysis shows association rather than direction, both SRSF9-to-partner and partner-to-SRSF9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SRSF9 versus SPPL3 in LSCC, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SRSF9→partner) and Y-score (partner→SRSF9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SPPL3 →	+0.564	+0.466	<.001	<.001	3	8
LSCC	POLE →	+0.745	+0.455	<.001	<.001	3	8
LSCC	KMT5A →	+0.700	+0.442	<.001	<.001	3	8
UCEC	GCN1 →	+0.880	+0.393	<.001	<.001	3	8
LSCC	DDX55 →	+0.549	+0.433	<.001	<.001	3	8
LSCC	RFC5 →	+0.911	+0.515	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,266 associations by consensus.

SRSF9 vs SPPL3 — LSCC

Explore this scatter interactively →